Winter-related illness is primarily driven by increased indoor proximity and dry air, which compromises the nasal passages' natural defenses—mucus, cilia, and microbiome—making nasal breathing and humidity essential for immune protection.
The prevalence of winter illnesses is a byproduct of environmental changes (shorter days, colder temperatures) that force humans into closer physical proximity and drier indoor environments, which in turn compromises the nasal passages' role as a primary immune barrier.
This summary is for anyone who finds themselves constantly "catching" colds or flus during the winter months or anyone interested in the physiological mechanics of respiratory health. It solves the mystery of why we get sick more often in the winter by identifying the specific environmental triggers—proximity and humidity—and provides a protocol to fortify your body's first line of defense: the nasal passages. After reading this, you will understand how to maintain your respiratory "fortress" through nasal breathing and humidity management.
Andrew Huberman argues that while we often blame "the cold" for illness, the true culprits are the behavioral and environmental shifts that occur during the winter months. Specifically, shorter days and lower temperatures lead to people spending more time indoors in closer physical proximity to one another. This proximity facilitates the transmission of viruses via sneezing, coughing, and even skin-to-skin contact (such as handshakes or wiping noses).
Furthermore, Huberman highlights a critical, often overlooked factor: the drying of the air. Indoor heating systems strip moisture from the air, which in turn dries out the nasal passages. Because the nose is the primary site of defense for the body—containing physical barriers like hairs (cilia), a protective mucosal lining, and a unique microbiome—drying out these passages leaves the body vulnerable to viral, bacterial, and fungal infections. To counter this, Huberman advocates for a "fortress" approach to respiratory health: prioritizing nasal breathing and ensuring the air you breathe is sufficiently humidified to keep these defenses intact.
What it is — The probability of contracting a cold or flu is directly related to physical distance. The closer you are to someone who is sneezing or coughing, the higher the probability of transmission. Why it matters — Understanding this allows you to recognize that "social distancing" isn't just a concept; it is a measurable physical barrier against pathogens. It validates the need to maintain distance from those who are actively symptomatic. In the book — Huberman notes that research has analyzed specific distances (e.g., one foot, three feet, six feet) to determine the probability of contraction, showing a "very direct relationship" where closer proximity equals higher risk.
What it is — There is no "safe" window where a person who is sneezing or coughing is not contagious. Why it matters — Many people believe they are not contagious during the early or late stages of a cold, but Huberman clarifies that if you are sneezing or coughing, you are actively transmitting the virus. In the book — Huberman states that "people's theories about when they are 'contagious' or 'not contagious' are rarely substantiated by the actual data."
What it is — Heating systems dry out the indoor air, which subsequently dries out the nasal passages. Why it matters — The nasal passages are the primary site of defense against infections. When they dry out, the physical and biological barriers they provide are compromised. In the book — Huberman uses a "GedankenExeriment" (thought experiment) comparing a walk on a cold, dry winter day to a walk on a humid summer day to help the reader "feel" the difference in air dryness.
What it is — The nose is a sophisticated defense system consisting of physical hairs (cilia), a mucosal lining that traps pathogens, and a microbiome of trillions of bacteria. Why it matters — These elements work together to trap viruses and bacteria before they can enter the deeper respiratory pathway or reach the brain. In the book — Huberman explains that the "hairs of your nostrils, the mucus itself, and the microbiome... actually serve to protect against many of the incoming infections." He also notes the proximity of the cribriform plate, a bony barrier near the nose, to the brain.
What it is — Mouth breathing is associated with a higher prevalence of allergies and a significantly higher likelihood of getting sick. Why it matters — Choosing to breathe through your nose rather than your mouth is a proactive way to maintain the integrity of your respiratory defenses. In the book — Huberman cites a study ("Association of oral breathing with dental malocclusions and general health in children") which shows that oral breathing is related to a "significantly higher prevalence of allergies and a significantly more likely getting sick."
What it is — Maintaining moisture in the air you breathe, especially during sleep, helps keep the nasal passages healthy and resistant to infection. Why it matters — While a humidifier won't stop a virus from being transmitted, it ensures your "fortress" is in the best possible condition to ward off the viruses you may have encountered. In the book — Huberman suggests using an air humidifier, particularly at night, to keep the mucosal lining of the nasal passages "thriving and intact."
What it is — A fever is an intentional immune response designed to heat up and destroy viruses. Why it matters — While high fevers can be dangerous, "blunting" a fever with medication can allow a virus to proliferate more easily. In the book — Huberman explains that "fever is an adaptation designed to destroy viruses," and warns against reducing core body temperature too much unless it reaches a dangerous level.
Use this to maintain the integrity of your respiratory barriers:
Use this to optimize your environment against winter illnesses:
Huberman asks you to imagine taking a brisk walk on a very cold winter day and "feeling" the dryness of the air, then compare it to a walk on a humid summer day. The lesson: This highlights how much moisture is stripped from the air in winter, which is the primary reason why indoor heating dries out our nasal passages.
Huberman addresses the common belief that people are "not contagious" during the beginning or end of a cold. The lesson: If you are sneezing or coughing, you are contagious. Data does not support the idea of a "safe" period during active symptoms.
Huberman mentions the proximity of the nasal passages to the brain, specifically the bony barrier called the cribriform plate. The lesson: This underscores why the nasal passages are such a critical first line of defense—they are the gatekeepers to the rest of your internal physiology.
"The closer you are to somebody who's sneezing or coughing, the higher probability that you will contract that cold or flu." Why it matters: This reinforces that physical proximity is the primary driver of transmission.
"The nasal passages represent a primary site of defense for viral infections like colds and flus but also bacterial infections and fungal infections." Why it matters: It shifts the focus from "fighting" a virus to "fortifying" the entry point.
"Oral breathing is related to a significantly higher prevalence of allergies and a significantly more likely getting sick and taking medication for being sick." Why it matters: This provides a clear, evidence-based reason to prefer nasal breathing.
#435 – Andrew Huberman Focus, Controversy, Politics, and RelationshipsLex Fridman Podcast
249 ‒ How the brain works, Andrew’s fascinating backstory, improving scientific literacy, and moreThe Peter Attia Drive
A Science-Supported Journaling Protocol to Improve Mental & Physical HealthHuberman Lab
Adderall, Stimulants & Modafinil for ADHD Short- & Long-Term EffectsHuberman Lab
ADHD & How Anyone Can Improve Their FocusHuberman Lab
AMA #1 Leveraging Ultradian Cycles, How to Protect Your Brain, Seed Oils Examined and MoreHuberman Lab
AMA #10 Benefits of Nature & “Grounding, Hearing Loss Research & Avoiding Altitude SicknessHuberman Lab
AMA #11 Improve Task Switching & Productivity and Reduce Brain FogHuberman Lab
AMA #12 Thoughts on Longevity Supplements (Resveratrol, NR, NMN, Etc.) & How to Improve MemoryHuberman Lab
AMA #14 2023 Philanthropy, Evening Routine, Light Therapy, Health Metrics & MoreHuberman Lab
AMA #15 Fluoride BenefitsRisks & Vagus Nerve StimulationHuberman Lab
AMA #16 Sleep, Vertigo, TBI, OCD, Tips for Travelers, Gut-Brain Axis & MoreHuberman Lab